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INFO:
Hirschsprung Disease Hirschsprung disease, also known as congenital aganglionic megacolon, is a congenital disorder where the colon lacks ganglion cells, leading to decreased bowel motility and stool obstruction. Ganglion cells help the parasympathetic nervous system stimulate peristalsis for normal bowel movements. In Hirschsprung disease, these nerve cells are missing, leading to severe constipation and colon enlargement. ⚠️ Key Symptoms to Know for Exams 👶 Newborns + Infants: No meconium within 48 hours of birth Constipation and abdominal distention Trouble feeding and bilious vomiting “Squirt sign” – explosive gas and watery stool after a digital rectal exam 🧒 Young Children: Chronic constipation and malnourishment Abdominal distention and pain Ribbon-like, foul-smelling stool 💬 Comment below if you’d like a part 2!